This course presents an integrated approach to the study of protein function. Topics include proteomic techniques in protein profiling, mass spectrometry, 2-D gel electrophoresis, yeast 2-hybrid analysis, protein chips, protein purification, imaging, surface plasmon resonance, calorimetry, bioinformatics and protein evolution, protein modifications and processing, interpretation and applications of 3-D structure, protein structure-function relationships. Three lecture hours per week; Fall. A. Mak. Offered jointly with BCHM-410 with additional work required. PREREQUISITES: BCHM-310 or 315*/316*/317* or permission of the instructor. EXCLUSION: BCHM-410, BCHM-810
This course presents an integrated approach to the study of protein function. Topics include proteomic techniques in protein profiling, mass spectrometry, 2-D gel electrophoresis, yeast 2-hybrid analysis, protein chips, protein purification, imaging, surface plasmon resonance, calorimetry, bioinformatics and protein evolution, protein modifications and processing, interpretation and applications of 3-D structure, protein structure-function relationships. Three lecture hours per week; Fall. A. Mak. Offered jointly with BCHM-410 with additional work required. PREREQUISITES: BCHM-310 or 315*/316*/317* or permission of the instructor. EXCLUSION: BCHM-410, BCHM-810
