Analysis of mechanisms of protein, lipid, and nucleic acid delivery and transport within cells. The course will examine processes of protein targeting, exocytosis, and endocytosis; molecular mechanisms of COP-and clathrin-mediated vesicle transport; and viral and SNARE-mediated membrane fusion. Lectures will present landmark experiments from classic papers, and student presentations will focus on recent research articles. The significance of these findings with respect to human disease and signal transduction will be considered. Prerequisite: MBB 322 and BISC 331/MBB 331 or permission of the instructor.
Analysis of mechanisms of protein, lipid, and nucleic acid delivery and transport within cells. The course will examine processes of protein targeting, exocytosis, and endocytosis; molecular mechanisms of COP-and clathrin-mediated vesicle transport; and viral and SNARE-mediated membrane fusion. Lectures will present landmark experiments from classic papers, and student presentations will focus on recent research articles. The significance of these findings with respect to human disease and signal transduction will be considered. Prerequisite: MBB 322 and BISC 331/MBB 331 or permission of the instructor.
