Modern organic reactions and reactive intermediates. Cations, free radicals, radical ions, carbenes, metallocarbenes, arynes, and transition-metal catalysis. Mechanisms, transition-state conformational analysis and stereoelectronic effects. Diastereoselectivity. The laboratory is focused on multistep organic synthesis, featuring reactions drawn from the lecture topics. Prerequisites: Chem 361 or consent of instructor. Students with credit for Chem 363 cannot take Chem 460 for credit.
Modern organic reactions and reactive intermediates. Cations, free radicals, radical ions, carbenes, metallocarbenes, arynes, and transition-metal catalysis. Mechanisms, transition-state conformational analysis and stereoelectronic effects. Diastereoselectivity. The laboratory is focused on multistep organic synthesis, featuring reactions drawn from the lecture topics. Prerequisites: Chem 361 or consent of instructor. Students with credit for Chem 363 cannot take Chem 460 for credit.
