(3 units). This course focuses on chemical approaches to solving problems in molecular and cellular biology. Emphasis will be placed on multidisciplinary approaches to understand biological pathways and biological systems. Recent advances in chemical tool development for systems biology will be highlighted. Approaches to target selection for chemical intervention will also be covered. Topics include: chemical approaches to genomics and proteomics; protein design and engineering; chemistry in cellular imaging; chemistry in biotechnology; chemical genetics; rational and combinatorial approaches to pathway intervention; metabolic engineering. Course Component: Lecture Prerequisites: BCH 2333, (CHM 2131 or CHM 2132). CHM 3120 and BCH 3170 or BIO 3170 are corequisite to BPS 4129.
(3 units). This course focuses on chemical approaches to solving problems in molecular and cellular biology. Emphasis will be placed on multidisciplinary approaches to understand biological pathways and biological systems. Recent advances in chemical tool development for systems biology will be highlighted. Approaches to target selection for chemical intervention will also be covered. Topics include: chemical approaches to genomics and proteomics; protein design and engineering; chemistry in cellular imaging; chemistry in biotechnology; chemical genetics; rational and combinatorial approaches to pathway intervention; metabolic engineering. Course Component: Lecture Prerequisites: BCH 2333, (CHM 2131 or CHM 2132). CHM 3120 and BCH 3170 or BIO 3170 are corequisite to BPS 4129.
