(3 units). Biopharmaceutics: General concepts and new developments in biopharmaceutics. Antibiotics and alternatives to antibiotics, antibodies, vaccines, microRNA, gene therapeutics and viral therapeutics. Fermentation and cell culture: cell growth kinetics; operation modes; expression of recombinant protein in bacteria, yeast, plant cells, insect cells, and mammalian cells. Bioseparation: solids/liquid separation (e.g., filtration, centrifugation, precipitation). Cell disruption; product recovery (distillation, membrane separation, ion exchange, affinity adsorption, solvent extraction, aqueous extraction, crystallization); concentration and drying (thin film evaporator, spray drying, frozen drying). Course Component: Lecture
(3 units). Biopharmaceutics: General concepts and new developments in biopharmaceutics. Antibiotics and alternatives to antibiotics, antibodies, vaccines, microRNA, gene therapeutics and viral therapeutics. Fermentation and cell culture: cell growth kinetics; operation modes; expression of recombinant protein in bacteria, yeast, plant cells, insect cells, and mammalian cells. Bioseparation: solids/liquid separation (e.g., filtration, centrifugation, precipitation). Cell disruption; product recovery (distillation, membrane separation, ion exchange, affinity adsorption, solvent extraction, aqueous extraction, crystallization); concentration and drying (thin film evaporator, spray drying, frozen drying). Course Component: Lecture
