This course exposes students to advanced topics in molecular biology including methods and strategies to utilize and analyze genes and their expression in cells and whole organisms. Topics include: delivery of genes into cells and animals and their applications; how to knock-out genes or knock-in new features to a gene; the molecular basis of disease including epigenetics; how to edit genomes with CRISPR/Cas9; single-cell analysis and technology; introduction to the various sub-disciplines in omics research and the differences between omics and hypothesis-driven research; and introduction to current approaches used in DNA forensics including ancestry-related DNA analyses.
This course exposes students to advanced topics in molecular biology including methods and strategies to utilize and analyze genes and their expression in cells and whole organisms. Topics include: delivery of genes into cells and animals and their applications; how to knock-out genes or knock-in new features to a gene; the molecular basis of disease including epigenetics; how to edit genomes with CRISPR/Cas9; single-cell analysis and technology; introduction to the various sub-disciplines in omics research and the differences between omics and hypothesis-driven research; and introduction to current approaches used in DNA forensics including ancestry-related DNA analyses.
