Review various biochemical, genetic and molecular biological approaches in the study of model unicellular eukaryotic microorganisms, primarily Saccharomyces yeasts. Emphasis will be on genome organization and manipulation, DNA metabolism, control of gene expression and cell cycle regulation. The complete yeast genome sequence and its application will be discussed. Experimental strategies developed in these lower eukaryotes for the study of other organisms will also be discussed. Weekly hours: 3 Lecture hoursPrerequisite(s): BIOL 226 (formerly BIOL 211) or permission of the instructor. Note: Students with credit for MICR 816 or MCIM 816 will not receive credit for this course.
Review various biochemical, genetic and molecular biological approaches in the study of model unicellular eukaryotic microorganisms, primarily Saccharomyces yeasts. Emphasis will be on genome organization and manipulation, DNA metabolism, control of gene expression and cell cycle regulation. The complete yeast genome sequence and its application will be discussed. Experimental strategies developed in these lower eukaryotes for the study of other organisms will also be discussed. Weekly hours: 3 Lecture hoursPrerequisite(s): BIOL 226 (formerly BIOL 211) or permission of the instructor. Note: Students with credit for MICR 816 or MCIM 816 will not receive credit for this course.