Considers how the activation of innate and adaptive immune mechanisms by microbial infections contribute to pathology. Topics include basic mechanisms of immune-cell migration and inflammation, functions of cytokines, antibody and cell-mediated hypersensitivity reactions and their role in disease processes as seen in allergies and autoimmunity. A portion is devoted transplantation immunology and to regulation of the immune response to tumors and parasites. Weekly hours: 3 Lecture hours and 3 Seminar/Discussion hoursPrerequisite(s): MCIM 321 (formerly MICR 421) or equivalent.Note: Students with credit for MCIM 823 may not take this course for credit.
Considers how the activation of innate and adaptive immune mechanisms by microbial infections contribute to pathology. Topics include basic mechanisms of immune-cell migration and inflammation, functions of cytokines, antibody and cell-mediated hypersensitivity reactions and their role in disease processes as seen in allergies and autoimmunity. A portion is devoted transplantation immunology and to regulation of the immune response to tumors and parasites. Weekly hours: 3 Lecture hours and 3 Seminar/Discussion hoursPrerequisite(s): MCIM 321 (formerly MICR 421) or equivalent.Note: Students with credit for MCIM 823 may not take this course for credit.