The principles and practice of whole-genome sequencing. Each student team will sequence an entire eukaryotic genome and analyze it. Topics will include: modern sequencing technology, yeast husbandry, genomic library construction and quality control, ânext-generationâ sequencing, sequence assembly using a reference genome, principles of genome organization, mutation detection and interpretation.
The principles and practice of whole-genome sequencing. Each student team will sequence an entire eukaryotic genome and analyze it. Topics will include: modern sequencing technology, yeast husbandry, genomic library construction and quality control, ânext-generationâ sequencing, sequence assembly using a reference genome, principles of genome organization, mutation detection and interpretation.