Regulatory mechanisms controlling gene expression in eukaryotes; students will read, discuss, and present the primary research literature in class. Topics include: assembly of the initiation complex; roles of transcription factors, co-activators and cis-acting regulatory elements; promoter escape; mechanisms that control elongation, termination and anti-termination of transcription; chromatin control of transcription.
Regulatory mechanisms controlling gene expression in eukaryotes; students will read, discuss, and present the primary research literature in class. Topics include: assembly of the initiation complex; roles of transcription factors, co-activators and cis-acting regulatory elements; promoter escape; mechanisms that control elongation, termination and anti-termination of transcription; chromatin control of transcription.
